When it comes to NetScaler End Point Analysis (EPA), Citrix provides a nice How-To Article as a starting point: https://support.citrix.com/pages/netscaler-gateway-epa.
ADC: Disable EPA / Full-VPN Popup
As you connect to your Gateway vServer using Microsoft Edge, ADC presents a popup windows to you: “Full VPN and EPA are not supported in Edge browser …”. In case …